Research

The DISCHARGE project examines for which patients with suspected coronary artery disease based on stable chest pain, cardiac computed tomography (CT) or cardiac catheterization is best suited. DISCHARGE has the capability to influence current standards and guidelines as well as coverage decisions and raises awareness among patients, health care providers, and decision-makers in Europe about the effectiveness and cost-effectiveness of cardiac CT.

DISCHARGE Trial results published in The New England Journal of Medicine

4. March 2022

The first DISCHARGE Trial results have been published in The New England Journal of Medicine (NEJM).

We would like to thank the entire DISCHARGE Trial Group, as well as the members of AG Dewey, and every patient at the 26 clinical sites in 16 European countries who helped in this exciting project.

Full trial results are available in The New England Journal of Medicine article here.

© Copyright NEJM

DISCHARGE Trial results published in Radiology

5. March 2024

DISCHARGE Trial results have been published in Radiology on “Coronary Artery Calcium Score Predicts Major Adverse Cardiovascular Events in Stable Chest Pain”.

Congratulations to the first authors of the publication, Federico Biavati and Prof. Luca Saba!

And of course, thanks to the entire DISCHARGE Trial Group and all participating patients.

The abstract of the article is available here.

© Radiology

DISCHARGE Trial results published in JAMA Cardiology

28. February 2024

DISCHARGE Trial results have been published in JAMA Cardiology on “Age and Computed Tomography and Invasive Coronary Angiography in Stable Chest Pain: A Prespecified Secondary Analysis of the DISCHARGE Randomized Clinical Trial”.

Congratulations to the first authors of the publication, Dr. Maria Bosserdt, Dr. Lina Serna-Higuita and Prof. Gudrun Feuchtner!

And of course, thanks to the entire DISCHARGE Trial Group and all participating patients.

The abstract of the article is available here.

© Copyright JAMA Cardiology

DISCHARGE Trial results published in Radiology

13. February 2024

DISCHARGE Trial results have been published in Radiology on “Effect of Body Mass Index on Effectiveness of CT versus Invasive Coronary Angiography in Stable Chest Pain: The DISCHARGE Trial”.

Congratulations to the first authors of the publication, Dr. Robert Sykes and Dr. Damien Collison!

And of course, thanks to the entire DISCHARGE Trial Group and all participating patients.

The abstract of the article is available here.

© Radiology

DISCHARGE Trial results published in European Radiology

22. November 2023

DISCHARGE Trial results have been published in European Radiology on “Impact of smoking in patients with suspected coronary artery disease in the randomised DISCHARGE trial”.

Congratulations to the first authors of the publication, Prof. Massimo Mancone, Aldo Vázquez Mézquita and Lucia Ilaria Birtolo!

And of course, thanks to the entire DISCHARGE Trial Group and all participating patients.

The abstract of the article is available here.

DISCHARGE Trial results published in Diabetes Care

19. September 2023

DISCHARGE Trial results have been published in Diabetes Care on “Computed Tomography Versus Invasive Coronary Angiography in Patients With Diabetes and Suspected Coronary Artery Disease”.

Congratulations to the first authors of the publication, Prof. Theodora Benedek and Dr. Viktoria Wieske!

And of course, thanks to the entire DISCHARGE Trial Group and all participating patients.

Full trial results are available in the Diabetes Care article here.

© Copyright Diabetes Care

DISCHARGE Trial results published in The British Medical Journal

19. October 2022

DISCHARGE Trial results on gender differences have been published in The British Medical Journal (The BMJ).

Full trial results are available in The British Medical Journal article here.

© Copyright The BMJ

Article about the pilot study in the DISCHARGE trial in European Radiology

9. September 2020

The scientific journal European Radiology published an article about the pilot study of the DISCHARGE trial. The article describes the accuracy of clinical pre-test probability for prediction of obstructive coronary artery disease in the pan-European trial setting. Please click on the image below to read the abstract of the article.

Article about the pilot study in the DISCHARGE trial in Health and Quality of Life Outcomes

14. May 2020

The scientific journal Health and Quality of Life Outcomes just published an article about the pilot study of the DISCHARGE trial as open access publication. The article describes the results of the analysis of the health-related quality of life of patients in the of the pan-European trial. Please click on the image below to read the abstract of the article or download the article.

© Health and Quality of Life Outcomes

Article about the pilot study in the DISCHARGE trial in European Radiology

16. December 2019

The scientific journal European Radiology just published an article about the pilot study of the DISCHARGE trial online. The article describes the analysis of the image quality and protocol adherence results of computed tomography and invasive coronary angiography of the pan-European trial. Please click on the image below to read the abstract of the article.

Presentation about the pilot study of the DISCHARGE trial at the Congress of the European Society of Radiology in Vienna

20 April 2017

An analysis of pretest probability assessment from the pilot study of the DISCHARGE trial was presented during the CTIR session of ECR 2017 by Sarah Feger.

group picture second day of CTIR 2017c


Article about the DISCHARGE trial in European Radiology

24 November 2016

The scientific journal European Radiology just published an article about the DISCHARGE trial online. The article describes the design and methods of the pan-European trial. Please click on the image below to read the abstract of the article.

european-radiology


Article about the DISCHARGE trial in The BMJ

10 April 2016

An article about the DISCHARGE trial and the ICMJE statement about data sharing was published in The BMJ.


Presentation about the pilot study of the DISCHARGE trial at the Congress of the European Society of Radiology in Vienna

10 April 2016

Pilot study image quality results of the DISCHARGE trial were presented during the CTIR session of ECR 2016 by Gianluca de Rubeis.


Presentation about the design and methods of the DISCHARGE trial at the Congress of the European Society of Radiology in Vienna

10 April 2015

Design and methods of the DISCHARGE trial presented during the CTIR session of ECR 2015 by Robert Haase.